Massive transfusions in Pediatrics

Abstract

Massive transfusion is the transfusion of more than 50 % of the total blood volume in 3 h; 100 % in 24 h or to replace the ongoing blood loss of more than 10% total blood volume per minute. Pediatric patients require massive transfusion in a variety of settings. There are limited data to support optimal mass transfusion strategies in children, the data is extrapolated from adults and is not the most convenient, however, about 15% of children require it. Current evidence suggests that in centers where massive protocol-based transfusions are performed, morbidity and mortality is much lower.